The Presence of dupA in Helicobacter pylori Is Not Significantly Associated with Duodenal Ulceration in Belgium, South Africa, China, or North America
نویسندگان
چکیده
منابع مشابه
The Helicobacter pylori duodenal ulcer promoting gene, dupA in China
BACKGROUND The prevalence of H. pylori is as high as 60-70% in Chinese population. Although duodenal ulcer and gastric cancer are both caused by H. pylori, they are at opposite ends of the spectrum and as such are considered mutually exclusive. Duodenal ulcer promoting (dupA) gene was reported to be associated with duodenal ulcer development. The aim of this study was to determine the prevalenc...
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We present a molecular epidemiologic study, based on an analysis of vacA, cagA and cag right end junction genotypes from 1042 Helicobacter pylori isolates, suggesting that H. pylori was present in the New World before Columbus. Eight Native Colombian and Alaskan strains possessed novel vacA and/or cagA gene structures and were more closely related to East Asian than to non-Asian H. pylori. Some...
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1 No. JMM/2011/038398 2 3 4 Significant association of dupA of Helicobacter pylori with duodenal ulcer development 5 in South East Indian Population 6 7 8 Jawed Alam 1 , Sankar Maiti 2 , Prachetash Ghosh 1 , Ronita De 1 , Abhijit Chowdhury 3 , 9 Suryasnata Das 4 , Ragini Macaden 4 , Harshad Devarbhavi 4 , T. Ramamurthy 1 , and Asish 10 K. Mukhopadhyay 1 * 11 12 13 14 15 1) National Institute of...
متن کاملDuodenal histology, ulceration, and Helicobacter pylori in the presence or absence of non-steroidal anti-inflammatory drugs.
Duodenitis and gastric metaplasia, which is often colonised by Helicobacter pylori (H pylori), are increasingly recognised for their importance in the pathogenesis of duodenal ulcers. The situation is not clear in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs), who have a higher risk of peptic ulceration. The aim of this study was to identify the duodenal histological abnorma...
متن کاملDetermination of Helicobacter pylori virulence-associated genes in duodenal ulcer and gastric biopsies
Background: Helicobacter pylori (H. pylori or Hp) has been strongly associated with the peptic ulcer diseases, chronic gastritis, ulcers, and gastric cancer. Genes associated with pathogenicity have been designated for H. pylori, and some of them appear to be related to more severe clinical consequences of the infection. The present study was conducted to determine cagA, vacA, cagE, iceA1, oipA...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2007
ISSN: 1058-4838,1537-6591
DOI: 10.1086/522177